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Title:

[Indication-Related Effectivity of Cervical Occlusion Techniques in Women with Threatening Preterm Birth].

Document type:
English Abstract; Journal Article; Article
Author(s):
Ohnolz, F; Schneider, K T M; Haller, B; Kuschel, B
Abstract:
The aim of this study was to identify which operation technique [total cervical occlusion (TMV), cerclage (C) or combination of both (TMV+C)] would lead to the greatest pregnancy prolongation in 3 different collectives of patients at risk (history of preterm birth, cervical insufficiency, prolapsing membranes). In this retrospective data collection, 200 cervical occlusions performed between 1997 and 2010 were analysed. In patients with a history of preterm birth/stillbirth (n=80) a prophylactic TMV increased the lifebirth rate from 35% without TMV to 95% with TMV (p<0.001). The risk diminuation after TMV was - 60% for stillbirth (p<0.001) and - 30% for preterm birth (p=0.01). In this subcollective the TMV seemed to be more effective in pregnancy prolongation (days) than C (139 vs. 113 days), however the combination of both (C+TMV) did not add much benefit (142 days). In patients with cervical insuffiency (n=86) the pregnancy could be prolonged by 82 (C), 79 (TMV) und 109 days (C+TMV) (p=0.003-0.017) and in patients with membrane prolaps (n=34) by 63 (C), 61 (TMV) und 76 (C+TMV) days. According to present data, the combination of cerclage and TMV has the highest benefit on pregnancy prolongation. This analysis should provide a basis for randomised controlled studies on this topic.
Journal title abbreviation:
Z Geburtshilfe Neonatol
Year:
2015
Journal volume:
219
Journal issue:
3
Pages contribution:
136-42
Language:
de
Fulltext / DOI:
doi:10.1055/s-0034-1390416
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25830499
Print-ISSN:
0948-2393
TUM Institution:
Frauenklinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie
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