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Titel:

Investigation of metabolic changes in STZ-induced diabetic rats with hyperpolarized [1-13C]acetate.

Dokumenttyp:
Journal Article
Autor(en):
Koellisch, Ulrich; Laustsen, Christoffer; Nørlinger, Thomas S; Østergaard, Jakob Appel; Flyvbjerg, Allan; Gringeri, Concetta V; Menzel, Marion I; Schulte, Rolf F; Haase, Axel; Stødkilde-Jørgensen, Hans
Abstract:
In the metabolism of acetate several enzymes are involved, which play an important role in free fatty acid oxidation. Fatty acid metabolism is altered in diabetes patients and therefore acetate might serve as a marker for pathological changes in the fuel selection of cells, as these changes occur in diabetes patients. Acetylcarnitine is a metabolic product of acetate, which enables its transport into the mitochondria for energy production. This study investigates whether the ratio of acetylcarni...     »
Zeitschriftentitel:
Physiol Rep
Jahr:
2015
Band / Volume:
3
Heft / Issue:
8
Sprache:
eng
Volltext / DOI:
doi:10.14814/phy2.12474
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26272734
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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