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Titel:

Light fluence normalization in turbid tissues via temporally unmixed multispectral optoacoustic tomography.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Deán-Ben, X Luís; Stiel, Andre C; Jiang, Yuanyuan; Ntziachristos, Vasilis; Westmeyer, Gil G; Razansky, Daniel
Abstract:
Discerning the accurate distribution of chromophores and biomarkers by means of optoacoustic imaging is commonly challenged by the highly heterogeneous excitation light patterns resulting from strong spatial variations of tissue scattering and absorption. Here we used the light-fluence dependent switching kinetics of reversibly switchable fluorescent proteins (RSFPs), in combination with real-time acquisition of volumetric multi-spectral optoacoustic data to correct for the light fluence distrib...     »
Zeitschriftentitel:
Opt Lett
Jahr:
2015
Band / Volume:
40
Heft / Issue:
20
Seitenangaben Beitrag:
4691-4
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26469596
Print-ISSN:
0146-9592
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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