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Title:

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Document type:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Journal Article
Author(s):
Jansen, Willemijn J; Ossenkoppele, Rik; Knol, Dirk L; Tijms, Betty M; Scheltens, Philip; Verhey, Frans R J; Visser, Pieter Jelle; Aalten, Pauline; Aarsland, Dag; Alcolea, Daniel; Alexander, Myriam; Almdahl, Ina S; Arnold, Steven E; Baldeiras, Inês; Barthel, Henryk; van Berckel, Bart N M; Bibeau, Kristen; Blennow, Kaj; Brooks, David J; van Buchem, Mark A; Camus, Vincent; Cavedo, Enrica; Chen, Kewei; Chetelat, Gael; Cohen, Ann D; Drzezga, Alexander; Engelborghs, Sebastiaan; Fagan, Anne M; Fladby,...     »
Abstract:
Cerebral amyloid-? aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.To use individual participant data meta-analysis to estimate the prevalence of amyloid pathology as measured with biomarkers in participants with normal cognition, subjective cognitive impairment (SCI), or mild cog...     »
Journal title abbreviation:
JAMA
Year:
2015
Journal volume:
313
Journal issue:
19
Pages contribution:
1924-38
Language:
eng
Fulltext / DOI:
doi:10.1001/jama.2015.4668
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25988462
Print-ISSN:
0098-7484
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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