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Title:

Violacein as a genetically-controlled, enzymatically amplified and photobleaching-resistant chromophore for optoacoustic bacterial imaging.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Jiang, Yuanyuan; Sigmund, Felix; Reber, Josefine; Deán-Ben, Xosé Luís; Glasl, Sarah; Kneipp, Moritz; Estrada, Héctor; Razansky, Daniel; Ntziachristos, Vasilis; Westmeyer, Gil G
Abstract:
There is growing interest in genetically expressed reporters for in vivo studies of bacterial colonization in the context of infectious disease research, studies of the bacterial microbiome or cancer imaging and treatment. To empower non-invasive high-resolution bacterial tracking with deep tissue penetration, we herein use the genetically controlled biosynthesis of the deep-purple pigment Violacein as a photobleaching-resistant chromophore label for in vivo optoacoustic (photoacoustic) imaging...     »
Journal title abbreviation:
Sci Rep
Year:
2015
Journal volume:
5
Pages contribution:
11048
Language:
eng
Fulltext / DOI:
doi:10.1038/srep11048
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26091543
Print-ISSN:
2045-2322
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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