Benutzer: Gast  Login
Titel:

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network.

Dokumenttyp:
Journal Article; Article
Autor(en):
Lee, Seonjoo; Viqar, Fawad; Zimmerman, Molly E; Narkhede, Atul; Tosto, Giuseppe; Benzinger, Tammie L S; Marcus, Daniel S; Fagan, Anne M; Goate, Alison; Fox, Nick C; Cairns, Nigel J; Holtzman, David M; Buckles, Virginia; Ghetti, Bernardino; McDade, Eric; Martins, Ralph N; Saykin, Andrew J; Masters, Colin L; Ringman, John M; Ryan, Natalie S; Forster, Stefan; Laske, Christoph; Schofield, Peter R; Sperling, Reisa A; Salloway, Stephen; Correia, Stephen; Jack, Clifford; Weiner, Michael; Bateman, Randa...     »
Abstract:
White matter hyperintensities (WMHs) are areas of increased signal on T2-weighted magnetic resonance imaging (MRI) scans that most commonly reflect small vessel cerebrovascular disease. Increased WMH volume is associated with risk and progression of Alzheimer's disease (AD). These observations are typically interpreted as evidence that vascular abnormalities play an additive, independent role contributing to symptom presentation, but not core features of AD. We examined the severity and distribu...     »
Zeitschriftentitel:
Ann Neurol
Jahr:
2016
Band / Volume:
79
Heft / Issue:
6
Seitenangaben Beitrag:
929-39
Sprache:
eng
Volltext / DOI:
doi:10.1002/ana.24647
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27016429
Print-ISSN:
0364-5134
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
 BibTeX