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Titel:

?/? coiled coils.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Hartmann, Marcus D; Mendler, Claudia T; Bassler, Jens; Karamichali, Ioanna; Ridderbusch, Oswin; Lupas, Andrei N; Hernandez Alvarez, Birte
Abstract:
Coiled coils are the best-understood protein fold, as their backbone structure can uniquely be described by parametric equations. This level of understanding has allowed their manipulation in unprecedented detail. They do not seem a likely source of surprises, yet we describe here the unexpected formation of a new type of fiber by the simple insertion of two or six residues into the underlying heptad repeat of a parallel, trimeric coiled coil. These insertions strain the supercoil to the breakin...     »
Zeitschriftentitel:
Elife
Jahr:
2016
Band / Volume:
5
Sprache:
eng
Volltext / DOI:
doi:10.7554/eLife.11861
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26771248
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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