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Document type:
Journal Article; Review 
Author(s):
Mueller, Tara C; Bachmann, Jeannine; Prokopchuk, Olga; Friess, Helmut; Martignoni, Marc E 
Title:
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia--can findings from animal models be translated to humans? 
Abstract:
Cachexia is a multi-factorial, systemic syndrome that especially affects patients with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival and quality of life. The most important clinical feature of cachexia is the excessive wasting of skeletal muscle mass. Currently, an effective treatment is still lacking and the search for therapeutic targets continues. Even though a substantial number of animal studies have contributed to a better understanding of the unde...    »
 
Journal title abbreviation:
BMC Cancer 
Year:
2016 
Journal volume:
16 
Pages contribution:
75 
Language:
eng 
TUM Institution:
Chirurgische Klinik und Poliklinik