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Title:

Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular Origin.

Document type:
Journal Article; Review; Review
Author(s):
Reichert, Maximilian; Blume, Karin; Kleger, Alexander; Hartmann, Daniel; von Figura, Guido
Abstract:
Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis, since it is usually diagnosed at advanced stages. In order to employ tools for early detection, a better understanding of the early stages of PDA development from its main precursors, pancreatic intraepithelial neoplasia (PanIN), and intraductal papillary mucinous neoplasm (IPMN) is needed. Recent studies on murine PDA models have identified a different exocrine origin for PanINs and IPMNs. In both processes,...     »
Journal title abbreviation:
Stem Cells Int
Year:
2016
Journal volume:
2016
Pages contribution:
9298535
Language:
eng
Fulltext / DOI:
doi:10.1155/2016/9298535
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26681957
Print-ISSN:
1687-966X
TUM Institution:
Chirurgische Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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