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Titel:

Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular Origin.

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Reichert, Maximilian; Blume, Karin; Kleger, Alexander; Hartmann, Daniel; von Figura, Guido
Abstract:
Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis, since it is usually diagnosed at advanced stages. In order to employ tools for early detection, a better understanding of the early stages of PDA development from its main precursors, pancreatic intraepithelial neoplasia (PanIN), and intraductal papillary mucinous neoplasm (IPMN) is needed. Recent studies on murine PDA models have identified a different exocrine origin for PanINs and IPMNs. In both processes,...     »
Zeitschriftentitel:
Stem Cells Int
Jahr:
2016
Band / Volume:
2016
Seitenangaben Beitrag:
9298535
Sprache:
eng
Volltext / DOI:
doi:10.1155/2016/9298535
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26681957
Print-ISSN:
1687-966X
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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