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Title:

The role of heat shock protein 70 (Hsp70) in radiation-induced immunomodulation.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Author(s):
Multhoff, Gabriele; Pockley, Alan G; Schmid, Thomas E; Schilling, Daniela
Abstract:
Despite enormous progress in radiation technologies (high precision image-guided irradiation, proton irradiation, heavy ion irradiation) and radiotherapeutic concepts (hypofractionated irradiation schemes), the clinical outcome of radiotherapy in locally advanced and metastasized tumors and in hypoxic tumors which are radiation-resistant remains unsatisfactory. Given their key influence on a number of biological and immunological parameters, this article considers the influence of irradiation-in...     »
Journal title abbreviation:
Cancer Lett
Year:
2015
Journal volume:
368
Journal issue:
2
Pages contribution:
179-84
Language:
eng
Fulltext / DOI:
doi:10.1016/j.canlet.2015.02.013
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25681671
Print-ISSN:
0304-3835
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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