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Titel:

Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Mykhaylyk, Olga; Sanchez-Antequera, Yolanda; Vlaskou, Dialechti; Cerda, Maria Belen; Bokharaei, Mehrdad; Hammerschmid, Edelburga; Anton, Martina; Plank, Christian
Abstract:
This chapter describes how to design and conduct experiments to deliver siRNA to adherent cell cultures in vitro by magnetic force-assisted transfection using self-assembled complexes of small interfering RNA (siRNA) and cationic lipids or polymers that are associated with magnetic nanoparticles (MNPs). These magnetic complexes are targeted to the cell surface by the application of a gradient magnetic field. A further development of the magnetic drug-targeting concept is combining it with an ult...     »
Zeitschriftentitel:
Methods Mol Biol
Jahr:
2015
Band / Volume:
1218
Seitenangaben Beitrag:
53-106
Sprache:
eng
Volltext / DOI:
doi:10.1007/978-1-4939-1538-5_5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25319646
Print-ISSN:
1064-3745
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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