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Titel:

Molecular targets and pathways involved in liver metastasis of colorectal cancer.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Weidle, Ulrich H; Birzele, Fabian; Krüger, Achim
Abstract:
We here summarize the current view of molecular mechanisms involved in the dissemination process of colorectal cancer cells to the liver as deduced from preclinical models. We focus on molecular aspects of the current understanding of the biology of liver metastases formation and survival, both being crucial for identification and validation of possible therapeutic targets and review the latest findings elucidating some features of the liver as a metastatic niche. In more detail, we outline the...     »
Zeitschriftentitel:
Clin Exp Metastasis
Jahr:
2015
Band / Volume:
32
Heft / Issue:
6
Seitenangaben Beitrag:
623-35
Sprache:
eng
Volltext / DOI:
doi:10.1007/s10585-015-9732-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26104118
Print-ISSN:
0262-0898
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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