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Title:

Functional fabrication of recombinant human collagen-phosphorylcholine hydrogels for regenerative medicine applications.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Mirazul Islam, M; C?pla, Vytautas; He, Chaoliang; Edin, Joel; Rakickas, Tomas; Kobuch, Karin; Ru?el?, ?ivil?; Jackson, W Bruce; Rafat, Mehrdad; Lohmann, Chris P; Valiokas, Ram?nas; Griffith, May
Abstract:
The implant-host interface is a critical element in guiding tissue or organ regeneration. We previously developed hydrogels comprising interpenetrating networks of recombinant human collagen type III and 2-methacryloyloxyethyl phosphorylcholine (RHCIII-MPC) as substitutes for the corneal extracellular matrix that promote endogenous regeneration of corneal tissue. To render them functional for clinical application, we have now optimized their composition and thereby enhanced their mechanical prop...     »
Journal title abbreviation:
Acta Biomater
Year:
2015
Journal volume:
12
Pages contribution:
70-80
Language:
eng
Fulltext / DOI:
doi:10.1016/j.actbio.2014.10.035
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25448347
Print-ISSN:
1742-7061
TUM Institution:
Klinik und Poliklinik für Augenheilkunde
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