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Titel:

Platelet Derived Growth Factor Has a Role in Pressure Induced Bladder Smooth Muscle Cell Hyperplasia and Acts in a Paracrine Way.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Preis, Laura; Herlemann, Annika; Adam, Rosalyn M; Dietz, Hans-Georg; Kappler, Roland; Stehr, Maximilian
Abstract:
Bladder outlet obstruction is a finding in many urological disorders, leading to bladder wall hyperplasia. We investigated platelet derived growth factor and its receptor in human bladder smooth muscle cells and urothelial cells exposed to hydrostatic pressure or PDGF in vitro.Bladder smooth muscle cells and urothelial cells were exposed to elevated hydrostatic pressure for 1 hour. The expression of PDGF and PDGFR was evaluated using reverse transcriptase-polymerase chain reaction and Western bl...     »
Zeitschriftentitel:
J Urol
Jahr:
2015
Band / Volume:
194
Heft / Issue:
6
Seitenangaben Beitrag:
1797-805
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.juro.2015.05.092
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26055827
Print-ISSN:
0022-5347
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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