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Title:

Neural plasticity in pancreatitis and pancreatic cancer.

Document type:
Journal Article; Review
Author(s):
Demir, Ihsan Ekin; Friess, Helmut; Ceyhan, Güralp O
Abstract:
Pancreatic nerves undergo prominent alterations during the evolution and progression of human chronic pancreatitis and pancreatic cancer. Intrapancreatic nerves increase in size (neural hypertrophy) and number (increased neural density). The proportion of autonomic and sensory fibres (neural remodelling) is switched, and are infiltrated by perineural inflammatory cells (pancreatic neuritis) or invaded by pancreatic cancer cells (neural invasion). These neuropathic alterations also correlate with...     »
Journal title abbreviation:
Nat Rev Gastroenterol Hepatol
Year:
2015
Journal volume:
12
Journal issue:
11
Pages contribution:
649-59
Language:
eng
Fulltext / DOI:
doi:10.1038/nrgastro.2015.166
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26460352
Print-ISSN:
1759-5045
TUM Institution:
Chirurgische Klinik und Poliklinik
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