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Title:

Short-term follow-up of disc cell therapy in a porcine nucleotomy model with an albumin-hyaluronan hydrogel: in vivo and in vitro results of metabolic disc cell activity and implant distribution.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Omlor, G W; Fischer, J; Kleinschmitt, K; Benz, K; Holschbach, J; Brohm, K; Anton, M; Guehring, T; Richter, W
Abstract:
Cell therapy would be favorably performed immediately after nucleotomy, to restore intervertebral disc functionality and to slow down disc degeneration. Promising results were reported from small animal models but remaining problems, especially in larger animals, include loss of vital cells due to annular damage at the injection site and detrimental intradiscal conditions. The aim of the present study was to optimize cell-based disc therapy using a new albumin-hyaluronan hydrogel together with b...     »
Journal title abbreviation:
Eur Spine J
Year:
2014
Journal volume:
23
Journal issue:
9
Pages contribution:
1837-47
Language:
eng
Fulltext / DOI:
doi:10.1007/s00586-014-3314-y
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24801573
Print-ISSN:
0940-6719
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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