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Title:

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells.

Document type:
Journal Article
Author(s):
Hütz, Katharina; Mejías-Luque, Raquel; Farsakova, Katarina; Ogris, Manfred; Krebs, Stefan; Anton, Martina; Vieth, Michael; Schüller, Ulrich; Schneider, Marlon R; Blum, Helmut; Wagner, Ernst; Jung, Andreas; Gerhard, Markus
Abstract:
Gastric cancer (GC) is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with Helicobacter pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric tumors. However, the molecular mechanisms involved in gastric carcinogenesis are still not fully understood, making it difficult to design targeted therapeutic approaches. Aberrant expr...     »
Journal title abbreviation:
Carcinogenesis
Year:
2014
Journal volume:
35
Journal issue:
4
Pages contribution:
942-50
Language:
eng
Fulltext / DOI:
doi:10.1093/carcin/bgt410
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24325912
Print-ISSN:
0143-3334
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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