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Title:

Novel high efficient coatings for anti-microbial surgical sutures using chlorhexidine in fatty acid slow-release carrier systems.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Obermeier, Andreas; Schneider, Jochen; Wehner, Steffen; Matl, Florian Dominik; Schieker, Matthias; von Eisenhart-Rothe, Rüdiger; Stemberger, Axel; Burgkart, Rainer
Abstract:
Sutures can cause challenging surgical site infections, due to capillary effects resulting in bacteria permeating wounds. Anti-microbial sutures may avoid these complications by inhibiting bacterial pathogens. Recently, first triclosan-resistances were reported and therefore alternative substances are becoming clinically relevant. As triclosan alternative chlorhexidine, the "gold standard" in oral antiseptics was used. The aim of the study was to optimize novel slow release chlorhexidine coating...     »
Journal title abbreviation:
PLoS ONE
Year:
2014
Journal volume:
9
Journal issue:
7
Pages contribution:
e101426
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0101426
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24983633
Print-ISSN:
1932-6203
TUM Institution:
Klinik und Poliklinik für Orthopädie und Sportorthopädie
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