Hospital staff are at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease (COVID-19) pandemic. This cross-sectional study aimed to determine the prevalence of SARS-CoV-2 infection in hospital staff at the University Hospital rechts der Isar in Munich, Germany, and identify modulating factors. Overall seroprevalence of SARS-CoV-2-IgG in 4,554 participants was 2.4%. Staff engaged in direct patient care, including those working in COVID-19 units, had a similar probability of being seropositive as non-patient-facing staff. Increased probability of infection was observed in staff reporting interactions with SARS-CoV-2‒infected coworkers or private contacts or exposure to COVID-19 patients without appropriate personal protective equipment. Analysis of spatiotemporal trajectories identified that distinct hotspots for SARS-CoV-2‒positive staff and patients only partially overlap. Patient-facing work in a healthcare facility during the SARS-CoV-2 pandemic might be safe as long as adequate personal protective equipment is used and infection prevention practices are followed inside and outside the hospital.      «

Hospital staff are at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease (COVID-19) pandemic. This cross-sectional study aimed to determine the prevalence of SARS-CoV-2 infection in hospital staff at the University Hospital rechts der Isar in Munich, Germany, and identify modulating factors. Overall seroprevalence of SARS-CoV-2-IgG in 4,554 participants was 2.4%. Staff engaged in direct patient care, including those working in COVI...     »

Institut für KI und Informatik in der Medizin (Prof. Rückert); Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland); Institut für Medizinische Mikrobiologie, Immunologie und Hygiene (Prof. Busch); Institut für Virologie (Prof. Protzer); Klinik und Poliklinik für Innere Medizin II, Gastroenterologie (Prof. Schmid); Klinik und Poliklinik für Neurologie (Prof. Hemmer); Lehrstuhl für Medizinische Informatik (Prof. Boeker); Professur für Nephrologie (Prof. Heemann); Roman Herzog Comprehensive Cancer Center     «

Institut für KI und Informatik in der Medizin (Prof. Rückert); Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland); Institut für Medizinische Mikrobiologie, Immunologie und Hygiene (Prof. Busch); Institut für Virologie (Prof. Protzer); Klinik und Poliklinik für Innere Medizin II, Gastroenterologie (Prof. Schmid); Klinik und Poliklinik für Neurologie (Prof. Hemmer); Lehrstuhl für Medizinische Informatik (Prof. Boeker); Professur für Nephrologie (Prof. Heemann); Roman Herzog Comprehens...     »