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Title:

Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS.

Document type:
Journal Article
Author(s):
Tsaktanis, Thanos; Beyer, Tobias; Nirschl, Lucy; Linnerbauer, Mathias; Grummel, Verena; Bussas, Mathias; Tjon, Emily; Mühlau, Mark; Korn, Thomas; Hemmer, Bernhard; Quintana, Francisco J; Rothhammer, Veit
Abstract:
OBJECTIVE: The relationship between serum aryl hydrocarbon receptor (AHR) agonistic activity levels with disease severity, its modulation over the course of relapsing-remitting MS (RRMS), and its regulation in progressive MS (PMS) are unknown. Here, we report the analysis of AHR agonistic activity levels in cross-sectional and longitudinal serum samples of patients with RRMS and PMS. METHODS: In a cross-sectional investigation, a total of 36 control patients diagnosed with noninflammatory diseas...     »
Journal title abbreviation:
Neurol Neuroimmunol Neuroinflamm
Year:
2021
Journal volume:
8
Journal issue:
2
Fulltext / DOI:
doi:10.1212/NXI.0000000000000933
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33361385
TUM Institution:
Klinik und Poliklinik für Neurologie; Molekulare Immunologie (Prof. Knolle)
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