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Chang, Yinshui;Bach, Luisa;Hasiuk, Marko;Wen, Lifen;Elmzzahi, Tarek;Tsui, Carlson;Gutiérrez-Melo, Nicolás;Steffen, Teresa;Utzschneider, Daniel T;Raj, Timsse;Jost, Paul Jonas;Heink, Sylvia;Cheng, Jingyuan;Burton, Oliver T;Zeiträg, Julia;Alterauge, Dominik;Dahlström, Frank;Becker, Jennifer-Christin;Kastl, Melanie;Symeonidis, Konstantinos;van Uelft, Martina;Becker, Matthias;Reschke, Sarah;Krebs, Stefan;Blum, Helmut;Abdullah, Zeinab;Paeschke, Katrin;Ohnmacht, Caspar;Neumann, Christian;Liston, Adrian;Meissner, Felix;Korn, Thomas;Hasenauer, Jan;Heissmeyer, Vigo;Beyer, Marc;Kallies, Axel;Jeker, Lukas T;Baumjohann, Dirk
TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf.
Sci Immunol
2024
9
93

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Afzali, Ali Maisam;Nirschl, Lucy;Sie, Christopher;Pfaller, Monika;Ulianov, Oleksii;Hassler, Tobias;Federle, Christine;Petrozziello, Elisabetta;Kalluri, Sudhakar Reddy;Chen, Hsin Hsiang;Tyystjärvi, Sofia;Muschaweckh, Andreas;Lammens, Katja;Delbridge, Claire;Büttner, Andreas;Steiger, Katja;Seyhan, Gönül;Ottersen, Ole Petter;Öllinger, Rupert;Rad, Roland;Jarosch, Sebastian;Straub, Adrian;Mühlbauer, Anton;Grassmann, Simon;Hemmer, Bernhard;Böttcher, Jan P;Wagner, Ingrid;Kreutzfeldt, Mario;Merkler, Doron;Pardàs, Irene Bonafonte;Schmidt Supprian, Marc;Buchholz, Veit R;Heink, Sylvia;Busch, Dirk H;Klein, Ludger;Korn, Thomas
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Nature
2024
627
8003
407-415

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Wolf, Elisabeth;Wicklein, Rebecca;Aly, Lilian;Schmaderer, Christoph;Afzali, Ali Maisam;Mardin, Christian;Korn, Thomas;Hemmer, Bernhard;Hofauer, Benedikt;Knier, Benjamin
Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren's syndrome.
J Neurol
2024
271
7
4610-4619

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Wertheimer, Tobias;Zwicky, Pascale;Rindlisbacher, Lukas;Sparano, Colin;Vermeer, Marijne;de Melo, Bruno Marcel Silva;Haftmann, Claudia;Rückert, Tamina;Sethi, Aakriti;Schärli, Stefanie;Huber, Anna;Ingelfinger, Florian;Xu, Caroline;Kim, Daehong;Häne, Philipp;Fonseca da Silva, André;Muschaweckh, Andreas;Nunez, Nicolas;Krishnarajah, Sinduya;Köhler, Natalie;Zeiser, Robert;Oukka, Mohamed;Korn, Thomas;Tugues, Sonia;Becher, Burkhard
IL-23 stabilizes an effector Treg cell program in the tumor microenvironment.
Nat Immunol
2024
25
3
512-524

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Baeten, Paulien;Hamad, Ibrahim;Hoeks, Cindy;Hiltensperger, Michael;Van Wijmeersch, Bart;Popescu, Veronica;Aly, Lilian;Somers, Veerle;Korn, Thomas;Kleinewietfeld, Markus;Hellings, Niels;Broux, Bieke
Rapamycin rescues loss of function in blood-brain barrier-interacting Tregs.
JCI Insight
2024
9
7

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Wicklein, Rebecca;Kreitner, Linus;Wild, Anna;Aly, Lilian;Rueckert, Daniel;Hemmer, Bernhard;Korn, Thomas;Menten, Martin J;Knier, Benjamin
Retinal small vessel pathology is associated with disease burden in multiple sclerosis.
Mult Scler
2024
30
7
812-819

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Schmidt, Henrik;Raj, Timsse;O'Neill, Thomas J;Muschaweckh, Andreas;Giesert, Florian;Negraschus, Arlinda;Hoefig, Kai P;Behrens, Gesine;Esser, Lena;Baumann, Christina;Feederle, Regina;Plaza-Sirvent, Carlos;Geerlof, Arie;Gewies, Andreas;Isay, Sophie E;Ruland, Jürgen;Schmitz, Ingo;Wurst, Wolfgang;Korn, Thomas;Krappmann, Daniel;Heissmeyer, Vigo
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
Proc Natl Acad Sci U S A
2023
120
48

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Scherer, Stefanie;Oberle, Susanne G;Kanev, Kristiyan;Gerullis, Ann-Katrin;Wu, Ming;de Almeida, Gustavo P;Puleston, Daniel J;Baixauli, Francesc;Aly, Lilian;Greco, Alessandro;Nizharadze, Tamar;Becker, Nils B;Hoesslin, Madlaina V;Donhauser, Lara V;Berner, Jacqueline;Chu, Talyn;McNamara, Hayley A;Esencan, Zeynep;Roelli, Patrick;Wurmser, Christine;Kleiter, Ingo;Vehreschild, Maria J G T;Mayer, Christoph A;Knolle, Percy;Klingenspor, Martin;Fumagalli, Valeria;Iannacone, Matteo;Prlic, Martin;Korn, Thomas;Pearce, Erika L;Höfer, Thomas;Schulz, Anna M;Zehn, Dietmar
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Nat Immunol
2023
24
3
501-515

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Bauer, Isabel J;Fang, Ping;Lämmle, Katrin F;Tyystjärvi, Sofia;Alterauge, Dominik;Baumjohann, Dirk;Yoon, Hongsup;Korn, Thomas;Wekerle, Hartmut;Kawakami, Naoto
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging.
Proc Natl Acad Sci U S A
2023
120
30

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Linnerbauer, Mathias;Beyer, Tobias;Nirschl, Lucy;Farrenkopf, Daniel;Lößlein, Lena;Vandrey, Oliver;Peter, Anne;Tsaktanis, Thanos;Kebir, Hania;Laplaud, David;Oellinger, Rupert;Engleitner, Thomas;Alvarez, Jorge Ivan;Rad, Roland;Korn, Thomas;Hemmer, Bernhard;Quintana, Francisco J;Rothhammer, Veit
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nat Commun
2023
14
1