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Title:

Long-term safety of replication-defective smallpox vaccine (MVA-BN) in atopic eczema and allergic rhinitis.

Document type:
Clinical Trial, Phase I; Journal Article; Article
Author(s):
Darsow, U; Sbornik, M; Rombold, S; Katzer, K; von Sonnenburg, F; Behrendt, H; Ring, J
Abstract:
Availability of a safe smallpox vaccine may be necessary under certain circumstances. Use of the old life virus vaccine was associated with serious adverse events, particularly in the setting of atopic eczema (AE) and immunodeficiency. Modified virus Ankara (MVA)-BN, a highly attenuated strain of vaccinia virus, was developed for vaccination with improved safety profile.A phase 1 study was conducted in 60 subjects without history of smallpox vaccination to gain experience with smallpox vaccinati...     »
Journal title abbreviation:
J Eur Acad Dermatol Venereol
Year:
2016
Journal volume:
30
Journal issue:
11
Pages contribution:
1971-1977
Language:
eng
Fulltext / DOI:
doi:10.1111/jdv.13797
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27357167
Print-ISSN:
0926-9959
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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