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Title:

Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network.

Document type:
Journal Article; Review
Author(s):
Eyerich, Stefanie; Eyerich, Kilian; Traidl-Hoffmann, Claudia; Biedermann, Tilo
Abstract:
The skin is the outermost barrier of the organism that ensures protection from external harm. Lately, our view of the skin has evolved from an inert mechanical barrier to an active organ that can sense danger signals and mount perfectly adapted defense measures in response to invading pathogens. This Review highlights the different levels of the cutaneous barrier (the microbiome, chemical, physical, and immune barriers), their characteristics, and functional, highly interconnected network of cel...     »
Journal title abbreviation:
Trends Immunol
Year:
2018
Journal volume:
39
Journal issue:
4
Pages contribution:
315-327
Language:
eng
Fulltext / DOI:
doi:10.1016/j.it.2018.02.004
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29551468
Print-ISSN:
1471-4906
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber); Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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