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Titel:

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.

Dokumenttyp:
Journal Article; Article
Autor(en):
Renner, Simone; Blutke, Andreas; Dobenecker, Britta; Dhom, Georg; Müller, Timo D; Finan, Brian; Clemmensen, Christoffer; Bernau, Maren; Novak, Istvan; Rathkolb, Birgit; Senf, Steffanie; Zöls, Susanne; Roth, Mirjam; Götz, Anna; Hofmann, Susanna M; Hrab? de Angelis, Martin; Wanke, Rüdiger; Kienzle, Ellen; Scholz, Armin M; DiMarchi, Richard; Ritzmann, Mathias; Tschöp, Matthias H; Wolf, Eckhard
Abstract:
The worldwide prevalence of obesity has increased to 10% in men and 15% in women and is associated with severe comorbidities such as diabetes, cancer, and cardiovascular disease. Animal models of obesity are central to experimental studies of disease mechanisms and therapeutic strategies. Diet-induced obesity (DIO) models in rodents have provided important insights into the pathophysiology of obesity and, in most instances, are the first in line for exploratory pharmacology studies. To deepen th...     »
Zeitschriftentitel:
Mol Metab
Jahr:
2018
Band / Volume:
16
Seitenangaben Beitrag:
180-190
Volltext / DOI:
doi:10.1016/j.molmet.2018.06.015
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30017782
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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