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Titel:

Mucin Coatings Prevent Tissue Damage at the Cornea-Contact Lens Interface

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Winkeljann, Benjamin; Boettcher, Kathrin; Balzer, Bizan N.; Lieleg, Oliver
Abstract:
With a prevalence of more than 10%, keratoconjunctivitis sicca (commonly known as dry eye syndrome) is one of the most frequent forms of ocular diseases; among contact lens wearers, this condition occurs even more often. Key components of the protective tear film are mucins, large glycoproteins that serve as molecular lubricants on many epithelial body surfaces. It is likely that, in the absence of a proper mucinous lubrication layer on the cornea surface, increased friction and tissue damage i...     »
Stichworte:
cornea; dry eye; lubrication; surface modification; tribology; ATOMIC-FORCE MICROSCOPY; FRICTION COEFFICIENT MEASUREMENT; OCULAR SURFACE; ARTICULAR-CARTILAGE; TAPPING-MODE; TRACT MUCINS; TEAR FILM; WEAR; LUBRICATION; XEROSTOMIA
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Advanced Materials Interfaces
Jahr:
2017
Band / Volume:
4
Heft / Issue:
19
Seitenangaben Beitrag:
1700186
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1002/admi.201700186
WWW:
http://onlinelibrary.wiley.com/doi/10.1002/admi.201700186/full
Verlag / Institution:
Wiley-Blackwell
E-ISSN:
2196-7350
Publikationsdatum:
25.07.2017
TUM Einrichtung:
Fachgebiet für Biomechanik, MW
Format:
Bild/Text
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