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Title:

Controlled nanoparticle release from a hydrogel by DNA-mediated particle disaggregation

Document type:
Zeitschriftenaufsatz
Author(s):
Nowald, C.; Käsdorf, B.T.; Lieleg, O.
Abstract:
For many pharmaceutical applications, it is important that different drugs are present in the human body at distinct timepoints. Typically, this is achieved by a sequential administration of different therapeutic agents. Amuch easier alternative would be to develop a drug delivery system containing a whole set of medically active compounds which are liberated in an orchestrated and controlled manner. Yet, such a controlled, sequential release of drugs from a carrier system that can be used i...     »
Keywords:
Drug delivery; DNA linker; Nanoparticles; Liposomes; Osmotic pressure
Journal title:
Journal of Controlled Release
Year:
2017
Journal volume:
246
Year / month:
2017-01
Pages contribution:
71-78
Covered by:
Scopus
Fulltext / DOI:
doi:10.1016/j.jconrel.2016.12.015
WWW:
http://www.sciencedirect.com/science/article/pii/S0168365916308136
Publisher:
Elsevier BV
E-ISSN:
0168-3659
Date of publication:
01.01.2017
TUM Institution:
Fachgebiet für Biomechanik
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