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Title:

Glucose modulation of spreading depression susceptibility.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Article
Author(s):
Hoffmann, Ulrike; Sukhotinsky, Inna; Eikermann-Haerter, Katharina; Ayata, Cenk
Abstract:
Spreading depression of Leão is an intense spreading depolarization (SD) wave associated with massive transmembrane ionic, water, and neurotransmitter shifts. Spreading depolarization underlies migraine aura, and occurs in brain injury, making it a potential therapeutic target. While susceptibility to SD can be modulated pharmacologically, much less is known about modulation by systemic physiological factors, such as the glycemic state. In this study, we systematically examined modulation of SD...     »
Journal title abbreviation:
J Cereb Blood Flow Metab
Year:
2013
Journal volume:
33
Journal issue:
2
Pages contribution:
191-5
Language:
eng
Fulltext / DOI:
doi:10.1038/jcbfm.2012.132
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22968322
Print-ISSN:
0271-678X
TUM Institution:
Klinik für Anästhesiologie (DHM)
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