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Titel:

FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Grundmann, Sebastian; Lindmayer, Christian; Hans, Felix P; Hoefer, Imo; Helbing, Thomas; Pasterkamp, Gerard; Bode, Christoph; de Kleijn, Dominique; Moser, Martin
Abstract:
Forkhead box (Fox) transcription factors are important regulators of cardiovascular development and several Fox-proteins have recently been shown to modulate embryonic and post-natal angiogenesis. However, the role of the FoxP subfamily, which is highly expressed in cardiovascular tissue, has not been investigated so far. Here, we show that the transcription factor FoxP1 is the highest expressed FoxP-protein in endothelial cells and that it is upregulated at the site of neovascularization during...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2013
Band / Volume:
8
Heft / Issue:
9
Seitenangaben Beitrag:
e70873
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0070873
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24023716
Print-ISSN:
1932-6203
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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