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Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Körner, Andreas; Schlegel, Martin; Kaussen, Torsten; Gudernatsch, Verena; Hansmann, Georg; Schumacher, Timo; Giera, Martin; Mirakaj, Valbona
Titel:
Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A.
Abstract:
The bidirectional communication between the immune and nervous system is important in regulating immune responses. Here we show that the adrenergic nerves of sympathetic nervous system orchestrate inflammation resolution and regenerative programs by modulating repulsive guidance molecule A (RGM-A). In murine peritonitis, adrenergic nerves and RGM-A show bidirectional activation by stimulating the mutual expression and exhibit a higher potency for the cessation of neutrophil infiltration; this r...     »
Zeitschriftentitel:
Nat Commun
Jahr:
2019
Band / Volume:
10
Heft / Issue:
1
Volltext / DOI:
doi:10.1038/s41467-019-08328-5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30733433
Print-ISSN:
2041-1723
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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