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Title:

Functional real-time optoacoustic imaging of middle cerebral artery occlusion in mice.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Kneipp, Moritz; Turner, Jake; Hambauer, Sebastian; Krieg, Sandro M; Lehmberg, Jens; Lindauer, Ute; Razansky, Daniel
Abstract:
Longitudinal functional imaging studies of stroke are key in identifying the disease progression and possible therapeutic interventions. Here we investigate the applicability of real-time functional optoacoustic imaging for monitoring of stroke progression in the whole brain of living animals.The middle cerebral artery occlusion (MCAO) was used to model stroke in mice, which were imaged preoperatively and the occlusion was kept in place for 60 minutes, after which optoacoustic scans were taken a...     »
Journal title abbreviation:
PLoS ONE
Year:
2014
Journal volume:
9
Journal issue:
4
Pages contribution:
e96118
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0096118
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24776997
Print-ISSN:
1932-6203
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos); Neurochirurgische Klinik und Poliklinik
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