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Title:

Peripheral monocytes of obese women display increased chemokine receptor expression and migration capacity.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Krinninger, P; Ensenauer, R; Ehlers, K; Rauh, K; Stoll, J; Krauss-Etschmann, S; Hauner, H; Laumen, H
Abstract:
The activation of peripheral immune cells and the infiltration of immune cells into adipose tissue in obesity are implicated in the development of type 2 diabetes mellitus.The aim of the study was to compare peripheral immune cells from obese and normal-weight women with regard to composition of immune cell subpopulations, surface expression of the chemokine receptors (CCRs) CCR2, CCR3, CCR5, and CXCR3 (chemokine (C-X-C motif) receptor 3) and cell-intrinsic migration capacity.This was a case-con...     »
Journal title abbreviation:
J Clin Endocrinol Metab
Year:
2014
Journal volume:
99
Journal issue:
7
Pages contribution:
2500-9
Language:
eng
Fulltext / DOI:
doi:10.1210/jc.2013-2611
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24606068
Print-ISSN:
0021-972X
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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