Ductoscopy is gaining increased importance in
the diagnosis of nipple discharge of unclear origin and intraductal
proliferation. For this reason we compared its diagnostic
value and feasibility to standard diagnostic methods.
Material and Methods: Ductoscopy was compared to
mammography, galactography, sonography, magnetic resonance
imaging (MRI), nipple smear, fine needle aspiration
cytology (FNAC), and high-speed core biopsy; feasibility,
sensitivity, and specificity were investigated for each
method. Results: 71 ductoscopies were evaluated, which
were followed up by open biopsies. Here, 3 invasive and 8
ductal carcinomas in situ were found, as well as 3 atypical
ductal hyperplasias, 44 papillomas/papillomatoses, and 13
benign findings. Feasibility of ductoscopy was in this series
100%. Duct sonography showed the highest sensitivity
(67.3%), followed by MRI (65.2%), galactography (56.3%),
ductoscopy (55.2%), and FNAC (51.9%). The highest specificity
was shown by FNAC, core biopsy, and galactography
(each 100.0%), followed by mammography (92.3%), nipple
smear (77.8%), ductoscopy, and duct sonography (each
61.5%); the lowest specificity was displayed by MRI (25.0%).
Conclusion: The results confirm that ductoscopy can be performed
within the same range of sensitivity and specificity
as other techniques. In order to make conclusive statements
about ductoscopy, especially in order to precisely define the
indications for this method, a prospective multicenter study
was initiated.
«
Ductoscopy is gaining increased importance in
the diagnosis of nipple discharge of unclear origin and intraductal
proliferation. For this reason we compared its diagnostic
value and feasibility to standard diagnostic methods.
Material and Methods: Ductoscopy was compared to
mammography, galactography, sonography, magnetic resonance
imaging (MRI), nipple smear, fine needle aspiration
cytology (FNAC), and high-speed core biopsy; feasibility,
sensitivity, and specificity were investigated for each...
»
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