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Titel:

Equine Recurrent Uveitis -- A Spontaneous Horse Model of Uveitis

Autor(en):
Deeg, Cornelia A.; Hauck, Stefanie M.; Amann, Barbara; Pompetzki, Dirk; Altmann, Frank; Raith, Albert; Schmalzl, Thomas; Stangassinger, Manfred; Ueffing, Marius
Abstract:
Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody-binding pattern of horses affected by spontaneous recurrent uveitis (ERU) to the retinal proteome. CRALBP also seems to be relevant to human autoimmune uveitis. Proteomic screening...     »
Stichworte:
Uveitis; spontaneous model; horse; Autoimmune; Target organ; Autoantigens; Proteomics; Regulated proteins
Zeitschriftentitel:
Ophthalmic Research
Jahr:
2008
Band / Volume:
40
Heft / Issue:
3-4
Seitenangaben Beitrag:
151--153
Volltext / DOI:
doi:10.1159/000119867
Verlag / Institution:
S. Karger AG
Verlagsort:
Basel, Switzerland
Print-ISSN:
1423-0259
E-ISSN:
1423-0259
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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