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Titel:

Hepatic transforming growth factor-? 1 stimulated clone-22 D1 controls systemic cholesterol metabolism.

Dokumenttyp:
Journal Article
Autor(en):
Jäger, Julia; Greiner, Vera; Strzoda, Daniela; Seibert, Oksana; Niopek, Katharina; Sijmonsma, Tjeerd P; Schäfer, Michaela; Jones, Allan; De Guia, Roldan; Martignoni, Marc; Dallinga-Thie, Geesje M; Diaz, Mauricio B; Hofmann, Thomas G; Herzig, Stephan
Abstract:
Disturbances in lipid homeostasis are hallmarks of severe metabolic disorders and their long-term complications, including obesity, diabetes, and atherosclerosis. Whereas elevation of triglyceride (TG)-rich very-low-density lipoproteins (VLDL) has been identified as a risk factor for cardiovascular complications, high-density lipoprotein (HDL)-associated cholesterol confers atheroprotection under obese and/or diabetic conditions. Here we show that hepatocyte-specific deficiency of transcription...     »
Zeitschriftentitel:
Mol Metab
Jahr:
2014
Band / Volume:
3
Heft / Issue:
2
Seitenangaben Beitrag:
155-66
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.molmet.2013.12.007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24634828
TUM Einrichtung:
Chirurgische Klinik und Poliklinik
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