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Title:

Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.

Document type:
Journal Article
Author(s):
Gehrmann, Mathias; Cervello, Melchiorre; Montalto, Giuseppe; Cappello, Francesco; Gulino, Alessandro; Knape, Clemens; Specht, Hanno M; Multhoff, Gabriele
Abstract:
Members of the heat shock protein 70 (HSP70) family play an important role in assisting protein folding, preventing protein aggregation and transport of proteins across membranes under physiological conditions. Following environmental (i.e., irradiation, chemotherapy), physiological (i.e., cell growth, differentiation), and pathophysiological (i.e., inflammation, tumorigenesis) stress, the synthesis of heat shock proteins (HSPs) is highly up-regulated, whereas protein synthesis in general is red...     »
Journal title abbreviation:
Front Immunol
Year:
2014
Journal volume:
5
Pages contribution:
307
Language:
eng
Fulltext / DOI:
doi:10.3389/fimmu.2014.00307
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25071768
Print-ISSN:
1664-3224
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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