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Titel:

Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Gehrmann, Mathias; Cervello, Melchiorre; Montalto, Giuseppe; Cappello, Francesco; Gulino, Alessandro; Knape, Clemens; Specht, Hanno M; Multhoff, Gabriele
Abstract:
Members of the heat shock protein 70 (HSP70) family play an important role in assisting protein folding, preventing protein aggregation and transport of proteins across membranes under physiological conditions. Following environmental (i.e., irradiation, chemotherapy), physiological (i.e., cell growth, differentiation), and pathophysiological (i.e., inflammation, tumorigenesis) stress, the synthesis of heat shock proteins (HSPs) is highly up-regulated, whereas protein synthesis in general is red...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2014
Band / Volume:
5
Seitenangaben Beitrag:
307
Sprache:
eng
Volltext / DOI:
doi:10.3389/fimmu.2014.00307
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25071768
Print-ISSN:
1664-3224
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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