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Title:

Reduced side effects by proton microchannel radiotherapy: study in a human skin model.

Document type:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Zlobinskaya, Olga; Girst, Stefanie; Greubel, Christoph; Hable, Volker; Siebenwirth, Christian; Walsh, Dietrich W M; Multhoff, Gabriele; Wilkens, Jan J; Schmid, Thomas E; Dollinger, Günther
Abstract:
The application of a microchannel proton irradiation was compared to homogeneous irradiation in a three-dimensional human skin model. The goal is to minimize the risk of normal tissue damage by microchannel irradiation, while preserving local tumor control through a homogeneous irradiation of the tumor that is achieved because of beam widening with increasing track length. 20 MeV protons were administered to the skin models in 10- or 50-?m-wide irradiation channels on a quadratic raster with dis...     »
Journal title abbreviation:
Radiat Environ Biophys
Year:
2013
Journal volume:
52
Journal issue:
1
Pages contribution:
123-33
Language:
eng
Fulltext / DOI:
doi:10.1007/s00411-012-0450-9
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23271171
Print-ISSN:
0301-634X
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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