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Title:

Surgical sutures filled with adipose-derived stem cells promote wound healing.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Reckhenrich, Ann Katharin; Kirsch, Bianca Manuela; Wahl, Elizabeth Ann; Schenck, Thilo Ludwig; Rezaeian, Farid; Harder, Yves; Foehr, Peter; Machens, Hans-Günther; Egaña, José Tomás
Abstract:
Delayed wound healing and scar formation are among the most frequent complications after surgical interventions. Although biodegradable surgical sutures present an excellent drug delivery opportunity, their primary function is tissue fixation. Mesenchymal stem cells (MSC) act as trophic mediators and are successful in activating biomaterials. Here biodegradable sutures were filled with adipose-derived mesenchymal stem cells (ASC) to provide a pro-regenerative environment at the injured site. Res...     »
Journal title abbreviation:
PLoS ONE
Year:
2014
Journal volume:
9
Journal issue:
3
Pages contribution:
e91169
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0091169
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24625821
Print-ISSN:
1932-6203
TUM Institution:
Klinik und Poliklinik für Orthopädie und Sportorthopädie; Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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