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Title:

Effective long-term treatment with bevacizumab for relapsed glioblastoma: case report and review of the literature.

Document type:
Journal Article
Author(s):
Schweneker, Katrin; Clemm, Christoph; Brügel, Melanie; Souvatzoglou, Michael; Hermisson, Mirjam; Schmidt-Graf, Friederike; Zimmer, Claus; Peschel, Christian; Jost, Philipp J
Abstract:
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Despite the use of optimized first-line therapy, GBM is still associated with a poor prognosis and an effective second-line therapy remains an important challenge in this patient population. In 2009, the US Food and Drug Administration (FDA) approved the monoclonal anti-VEGF-antibody bevacizumab for the treatment of relapsed GBM after two phase-II studies showed its efficacy and safety, alone or in combinat...     »
Journal title abbreviation:
Exp Hematol Oncol
Year:
2014
Journal volume:
3
Pages contribution:
29
Language:
eng
Fulltext / DOI:
doi:10.1186/2162-3619-3-29
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25954595
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Neurologische Klinik und Poliklinik
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