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Title:

Gaussian Mixture Models and Model Selection for [18F] Fluorodeoxyglucose Positron Emission Tomography Classification in Alzheimer's Disease.

Document type:
Journal Article
Author(s):
Li, Rui; Perneczky, Robert; Yakushev, Igor; Forster, Stefan; Kurz, Alexander; Drzezga, Alexander; Kramer, Stefan
Abstract:
We present a method to discover discriminative brain metabolism patterns in [18F] fluorodeoxyglucose positron emission tomography (PET) scans, facilitating the clinical diagnosis of Alzheimer's disease. In the work, the term "pattern" stands for a certain brain region that characterizes a target group of patients and can be used for a classification as well as interpretation purposes. Thus, it can be understood as a so-called "region of interest (ROI)". In the literature, an ROI is often found b...     »
Journal title abbreviation:
PLoS ONE
Year:
2014
Journal volume:
10
Journal issue:
4
Pages contribution:
e0122731
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0122731
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25919662
Print-ISSN:
1932-6203
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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