User: Guest  Login
Title:

Utility of ATP7B in Prediction of Response to Platinum-based Chemotherapy in Urothelial Bladder Cancer.

Document type:
Journal Article
Author(s):
Schmid, SC; Schuster, T; Horn, T; Gschwend, J; Treiber, U; Weirich, G
Abstract:
Platinum-based chemotherapy is the treatment of choice for metastatic urothelial carcinoma, which is limited by primary and secondary resistance of the tumour. The Cu(2+) transporting beta polypeptide ATPase (ATP7B) is believed to play a role in this resistance. The aim of this study was to screen the ATP7B gene for mutations and loss of heterozygosity in bladder cancer and to evaluate their impact on chemotherapy resistance.DNA extracted from 17 patients with metastatic bladder cancer was analy...     »
Journal title abbreviation:
Anticancer Res
Year:
2013
Journal volume:
33
Journal issue:
9
Pages contribution:
3731-7
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24023303
Print-ISSN:
0250-7005
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie; Urologische Klinik und Poliklinik
 BibTeX