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Title:

Effect of antiresorptive drugs on bony turnover in the jaw: denosumab compared with bisphosphonates.

Document type:
Journal Article
Author(s):
Ristow, Oliver; Gerngroß, Carlos; Schwaiger, Markus; Hohlweg-Majert, Bettina; Kehl, Victoria; Jansen, Heike; Hahnefeld, Lilian; Koerdt, Steffen; Otto, Sven; Pautke, Christoph
Abstract:
Osteonecrosis of the jaw as a result of treatment with receptor activators of nuclear factor kappa-B ligand (RANKL) inhibitors (denosumab) is a new type of bony necrosis, the exact pathogenesis of which is unknown. Our aim was to find out whether the turnover of bone in the jaw is increased after denosumab has been given compared with other skeletal sites, and if that turnover might have a role in denosumab-related osteonecrosis of the jaw (DRONJ). Bone scintigraphic images of 45 female patients...     »
Journal title abbreviation:
Br J Oral Maxillofac Surg
Year:
2014
Journal volume:
52
Journal issue:
4
Pages contribution:
308-13
Language:
eng
Fulltext / DOI:
doi:10.1016/j.bjoms.2014.01.021
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24582013
Print-ISSN:
0266-4356
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Nuklearmedizin
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