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Titel:

Site-selective immobilization of anti-CD34 antibodies to poly(l-lactide) for endovascular implant surfaces.

Dokumenttyp:
journal article
Autor(en):
Petersen, Svea, S; Strohbach, Anne, A; Busch, Raila, R; Felix, Stephan B, SB; Schmitz, Klaus-Peter, KP; Sternberg, Katrin, K
Abstract:
Aiming at a speed up of the re-endothelialization process of biodegradable endovascular implants, novel approaches for the functionalization of poly(l-lactide) (PLLA) with anti-CD34 antibodies were established. We propose a three-step process involving PLLA surface activation with functional amino groups, attachment of a protein repelling peptide spacer, and covalent random or site-selective immobilization of the antibodies. Obtainable antibody surface densities and antigen binding capacities we...     »
Zeitschriftentitel:
J Biomed Mater Res B Appl Biomater
Jahr:
2014
Band / Volume:
102
Heft / Issue:
2
Seitenangaben Beitrag:
345-55
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24000221
Print-ISSN:
1552-4973
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie
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