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Titel:

Osteogenic differentiation of mesenchymal stem cells in fibrin-hydroxyapatite matrix in a 3-dimensional mesh scaffold.

Dokumenttyp:
Journal Article
Autor(en):
Jung, Ole; Hanken, Henning; Smeets, Ralf; Hartjen, Philip; Friedrich, Reinhard E; Schwab, Bettina; Gröbe, Alexander; Heiland, Max; Al-Dam, Ahmed; Eichhorn, Wolfgang; Sehner, Susanne; Kolk, Andreas; Wöltje, Michael; Stein, Jamal M
Abstract:
To explore the feasibility of culturing mesenchymal stem cells in an hydroxyapatite-fibrin matrix held by a mesh scaffold and inducing osteogenic differentiation of these cells. The aim was to obtain bone-material in vitro in a desired form.Rat mesenchymal stem cells were mixed with fibrin and nanocrystalline hydroxyapatite in tubular scaffolds constructed from a poly(L-lactic acid) mesh, and cultured under standard and osteogenic differentiating conditions. Cell viability, cytotoxicity and alka...     »
Zeitschriftentitel:
In Vivo
Jahr:
2014
Band / Volume:
28
Heft / Issue:
4
Seitenangaben Beitrag:
477-82
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24982212
Print-ISSN:
0258-851X
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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