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Titel:

Prefabrication of 3D cartilage contructs: towards a tissue engineered auricle--a model tested in rabbits.

Dokumenttyp:
journal article
Autor(en):
von Bomhard, Achim, A; Veit, Johannes, J; Bermueller, Christian, C; Rotter, Nicole, N; Staudenmaier, Rainer, R; Storck, Katharina, K; The, Hoang Nguyen, HN
Abstract:
The reconstruction of an auricle for congenital deformity or following trauma remains one of the greatest challenges in reconstructive surgery. Tissue-engineered (TE) three-dimensional (3D) cartilage constructs have proven to be a promising option, but problems remain with regard to cell vitality in large cell constructs. The supply of nutrients and oxygen is limited because cultured cartilage is not vascular integrated due to missing perichondrium. The consequence is necrosis and thus a loss of...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2013
Band / Volume:
8
Heft / Issue:
8
Seitenangaben Beitrag:
e71667
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23951215
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie ; Hals-, Nasen-, Ohrenklinik und Poliklinik
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