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Titel:

Cell-free carrier system for localized delivery of peripheral blood cell-derived engineered factor signaling: towards development of a one-step device for autologous angiogenic therapy.

Dokumenttyp:
Journal Article
Autor(en):
Hadjipanayi, E; Bauer, A T; Moog, P; Salgin, B; Kuekrek, H; Fersch, B; Hopfner, U; Meissner, T; Schlüter, A; Ninkovic, M; Machens, H G; Schilling, A F
Abstract:
Spatiotemporally-controlled delivery of hypoxia-induced angiogenic factor mixtures has been identified by this group as a promising strategy for overcoming the limited ability of chronically ischemic tissues to generate adaptive angiogenesis. We previously developed an implantable, as well as an injectable system for delivering fibroblast-produced factors in vivo. Here, we identify peripheral blood cells (PBCs) as the ideal factor-providing candidates, due to their autologous nature, ease of har...     »
Zeitschriftentitel:
J Control Release
Jahr:
2013
Band / Volume:
169
Heft / Issue:
1-2
Seitenangaben Beitrag:
91-102
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jconrel.2013.04.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23603614
Print-ISSN:
0168-3659
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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