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Titel:

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Mayer, A; Höckel, M; Schlischewsky, N; Schmidberger, H; Horn, L-C; Vaupel, P
Abstract:
Experimental studies have established a causal connection between tumour hypoxia, hypoxia-associated proteome changes and downregulation of E-cadherin, the final common pathway of epithelial-to-mesenchymal transition (EMT). Our study aimed at elucidating the interrelationship of these processes in cancers of the uterine cervix in vivo.Tumour oxygenation was assessed in 48 squamous cell carcinomas (SCC) of the uterine cervix using polarographic needle electrodes. The expression pattern of E-cadhe...     »
Zeitschriftentitel:
Br J Cancer
Jahr:
2013
Band / Volume:
108
Heft / Issue:
2
Seitenangaben Beitrag:
402-8
Sprache:
eng
Volltext / DOI:
doi:10.1038/bjc.2012.570
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23322209
Print-ISSN:
0007-0920
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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