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Titel:

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Lang, PA; Xu, HC; Grusdat, M; McIlwain, DR; Pandyra, AA; Harris, IS; Shaabani, N; Honke, N; Kumar Maney, S; Lang, E; Pozdeev, VI; Recher, M; Odermatt, B; Brenner, D; Häussinger, D; Ohashi, PS; Hengartner, H; Zinkernagel, RM; Mak, TW; Lang, KS
Abstract:
Cluster of differentiation (CD)8(+) T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated levels of reactive oxygen species (ROS) have been reported during virus infections. However, the role of ROS in T-cell-mediated immunopathology remains unclear. Here we used the murine lymphocytic choriomeningitis virus to explore the role of ROS during the processes of virus elimination...     »
Zeitschriftentitel:
Cell Death Differ
Jahr:
2013
Band / Volume:
20
Heft / Issue:
4
Seitenangaben Beitrag:
649-58
Sprache:
eng
Volltext / DOI:
doi:10.1038/cdd.2012.167
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23328631
Print-ISSN:
1350-9047
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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