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- Document type:
- Journal Article; Research Support, Non-U.S. Gov't
- Author(s):
- Neubauer, S; Rechenmacher, F; Beer, AJ; Curnis, F; Pohle, K; D'Alessandria, C; Wester, HJ; Reuning, U; Corti, A; Schwaiger, M; Kessler, H
- Title:
- Selective imaging of the angiogenic relevant integrins ?5?1 and ?v?3.
- Abstract:
- Pattern seekers: For the two angiogenic relevant integrins ?5?1 and ?v?3, functionalized derivatives of the selective antagonists 1 and 2 could target and discriminate between tumor cells in vivo based on their different integrin patterns and also delay tumor growth in vivo. In addition, the first ?5?1-selective integrin antagonist that enables specific molecular imaging by positron emission tomography was developed.
- Journal title abbreviation:
- Angew Chem Int Ed Engl
- Year:
- 2013
- Journal volume:
- 52
- Journal issue:
- 44
- Pages contribution:
- 11656-9
- Language:
- eng
- Fulltext / DOI:
- doi:10.1002/anie.201306376
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/24115324
- Print-ISSN:
- 1433-7851
- TUM Institution:
- Frauenklinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin
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